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Procyanidin B2 gallate regulates TNF-α production from T cells through inhibiting glycolytic activity via mTOR-HIF-1 pathway

  • Published:2020-07 Issue: Volume:177 Page:113952
  • ISSN:0006-2952
  • Container-title:Biochemical Pharmacology
  • language:en
  • Short-container-title:Biochemical Pharmacology

Author:

Endo Katsunori,Matsui Rina,Sugiyama Momona,Asami Takuya,Inaba Chihiro,Kobayashi Shuhei,Makabe HidefumiORCID,Tanaka Sachi

Funder

Grant-in-Aid for Scientific Research

Japan Society for the Promotion of Science

Lotte Foundation

KOSÉ Cosmetology Research Foundation

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference35 articles.

1. From TCR engagement to T cell activation: a kinetic view of T cell behavior;Lanzavecchia;Cell,1999

2. Plasticity of T-cell phenotype and function: the T helper type 17 example;Peck;Immunology,2010

3. The role of TNF-alpha in T-cell-mediated inflammation depends on the Th1/Th2 cytokine balance;Hernandez-Pando;Immunology,1994

4. Tumor necrosis factor: biology and therapeutic inhibitors;Papadakis;Gastroenterology,2000

5. The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease;Leung;Cell Mol. Immunol.,2010
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