Sorafenib suppresses TGF-β responses by inducing caveolae/lipid raft-mediated internalization/degradation of cell-surface type II TGF-β receptors: Implications in development of effective adjunctive therapy for hepatocellular carcinoma-Reference-Cited by-同舟云学术

Sorafenib suppresses TGF-β responses by inducing caveolae/lipid raft-mediated internalization/degradation of cell-surface type II TGF-β receptors: Implications in development of effective adjunctive therapy for hepatocellular carcinoma

Published:2018-08 Issue: Volume:154 Page:39-53
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Chung Chih-Ling,Wang Shih-Wei,Sun Wei-Chih,Shu Chih-Wen,Kao Yu-Chen,Shiao Meng-Shin,Chen Chun-Lin

Funder

Ministry of Science and Technology of Taiwan

KMU Stem Cell Center

NSYSU-KVGH

NSYSU-KMU

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference56 articles.

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3. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5;Liu;Cancer Res.,2006

4. VEGFR-2 inhibitors and apoptosis inducers: synthesis and molecular design of new benzo[g]quinazolin bearing benzenesulfonamide moiety;Ghorab;J. Enzym. Inhib. Med. Chem.,2017

5. Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation;Chen;Cell Death Dis.,2013

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