Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration-Reference-Cited by-同舟云学术

Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration

Published:2012-01 Issue:2 Volume:83 Page:199-206
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Chu Rong,Terrano David T.,Chambers Timothy C.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference24 articles.

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4. NBK/BIK antagonizes Mcl-1 and Bcl-xL and activates Bak-mediated apoptosis in response to protein synthesis inhibition;Shimazu;Genes Dev,2007

5. The Bcl-2 apoptotic switch in cancer development and therapy;Adams;Oncogene,2007

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