PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3-Reference-Cited by-同舟云学术

PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3

Published:2021-10 Issue: Volume:192 Page:114736
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Sun Mingming,Sheng Hao,Wu Tingfeng,Song Jiaqi,Sun Huanran,Wang Yingzhi,Wang Jiyan,Li Zhen,Zhao Huifang,Tan Junzhen,Li Yanping,Chen Guo,Huang Qingrong,Zhang Yuan,Lan Bei,Liu Shuangping,Shan Changliang,Zhang Shuai

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference20 articles.

1. PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion;Ahn;J Biol Chem,2004

2. PIKE-A is amplified in human cancers and prevents apoptosis by up-regulating Akt;Ahn;Proc Natl Acad Sci U S A,2004

3. The roles of PIKE in tumorigenesis;Qi;Acta Pharmacol Sin,2013

4. PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis;Rong;Nat Neurosci,2003

5. Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation;Zhang;Cell Death Dis,2019

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