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Matrix degradation in osteoarthritis primes the superficial region of cartilage for mechanical damage

  • Published:2018-09 Issue: Volume:78 Page:320-328
  • ISSN:1742-7061
  • Container-title:Acta Biomaterialia
  • language:en
  • Short-container-title:Acta Biomaterialia

Author:

Cooke Megan E.,Lawless Bernard M.,Jones Simon W.,Grover Liam M.

Funder

EPSRC Sci-Phy-4-Health Centre

Arthritis Research UK

Publisher

Elsevier BV

Subject

Molecular Biology,Biomedical Engineering,Biochemistry,Biomaterials,General Medicine,Biotechnology

Reference52 articles.

1. Developing anti-inflammatory therapeutics for patients with osteoarthritis;Philp;Rheumatology (Oxford, England),2017

2. Mechanisms involved in cartilage proteoglycan catabolism;Caterson;Matrix Biol.,2000

3. Mitogen-activated protein kinase-activated protein kinase 2 (MK2) modulates key biological pathways associated with OA disease pathology;Jones;Osteoarthritis Cartilage,2009

4. Inflammation in osteoarthritis;Goldring;Curr. Opin. Rheumatol.,2011

5. The hallmarks of osteoarthritis and the potential to develop personalised disease-modifying pharmacological therapeutics;Tonge;Osteoarthritis Cartilage,2014

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