Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy

Author:

Merckx Pieterjan,De Backer Lynn,Van Hoecke Lien,Guagliardo Roberta,Echaide Mercedes,Baatsen Pieter,Olmeda Bárbara,Saelens Xavier,Pérez-Gil Jésus,De Smedt Stefaan C.,Raemdonck Koen

Funder

Spanish Ministry of Economy

FWO

Ghent University

IWT

Publisher

Elsevier BV

Subject

Molecular Biology,Biomedical Engineering,Biochemistry,Biomaterials,General Medicine,Biotechnology

Reference38 articles.

1. WHO-The top 10 causes of death. http://www.who.int (accessed 10.07. 2015).

2. Current prospects for RNA interference-based therapies;Davidson;Nat. Rev. Genet.,2011

3. Knocking down disease: a progress report on siRNA therapeutics;Wittrup;Nat. Rev. Genet.,2015

4. Delivery of RNAi therapeutics to the airways-from bench to bedside;Qiu;Molecules,2016

5. Bio-inspired materials in drug delivery: Exploring the role of pulmonary surfactant in siRNA inhalation therapy;De Backer;J. Controlled Release,2015

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