Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations-Reference-Cited by-同舟云学术

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Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations

Published:2017-02 Issue: Volume:118 Page:119-127
ISSN:0039-128X
Container-title:Steroids
language:en
Short-container-title:Steroids

Author:

Viktorsson Elvar Örn,Gabrielsen Mari,Kumarachandran Nugalya,Sylte Ingebrigt,Rongved Pål,Åstrand Ove Alexander Høgmoen,Kase Eili Tranheim

Funder

University of Oslo

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry

Reference45 articles.

1. Selective liver X receptor modulators (SLiMs): what use in human health?;Viennois;Mol. Cell. Endocrinol.,2012

2. Liver X receptor biology and pharmacology: new pathways, challenges and opportunities;Jakobsson;Trends Pharmacol. Sci.,2012

3. An oxysterol signalling pathway mediated by the nuclear receptor LXR[alpha];Janowski;Nature,1996

4. Liver X receptors in lipid metabolism: opportunities for drug discovery;Hong;Nat. Rev. Drug Discov.,2014

5. Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ;Janowski;Proc. Natl. Acad. Sci. U.S.A.,1999

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3. Novel Synthetic Access to 24a-Homochol-5-en-24a-oate Scaffold from Stigmasterol;Organic Preparations and Procedures International;2021-10-01

4. Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold;Bioorganic & Medicinal Chemistry Letters;2019-02

5. Recent Advances in the Medicinal Chemistry of Liver X Receptors;Journal of Medicinal Chemistry;2018-07-13

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