Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold-Reference-Cited by-同舟云学术

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Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold

Published:2019-02 Issue:3 Volume:29 Page:449-453
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Goher Shaimaa S.,Griffett Kristine,Hegazy Lamees,Elagawany Mohamed,Arief Mohamed M.H.,Avdagic Amer,Banerjee Subhashis,Burris Thomas P.,Elgendy Bahaa

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Liver X receptor biology and pharmacology: new pathways, challenges and opportunities

2. Recent Advances in the Medicinal Chemistry of Liver X Receptors;El-Gendy;J Med Chem.,2018

3. Safety, Pharmacokinetics, and Pharmacodynamics of Single Doses of LXR-623, a Novel Liver X-Receptor Agonist, in Healthy Participants

4. Indazole-Based Liver X Receptor (LXR) Modulators with Maintained Atherosclerotic Lesion Reduction Activity but Diminished Stimulation of Hepatic Triglyceride Synthesis

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1. Structure-Guided Design, Synthesis, and Biological Evaluation of Peripheral Anionic Site Selective and Brain Permeable Novel Oxadiazole-Piperazine Conjugates against Alzheimer’s Disease with Antioxidant Potential;ACS Omega;2024-04-11

2. Exploring the Antifungal Potential of 1,2,4-Triazole Derivatives: A Comprehensive Study on Design and Synthesis;Eurasian Journal of Chemistry;2023-12-30

3. Identification of Novel Compounds Targeting the Liver X Receptor (LXR): in-silico studies, screening, molecular docking, and chemico-pharmacokinetic analysis;2023-12-06

4. Dietary Phenolic Compounds Exert Some of Their Health-Promoting Bioactivities by Targeting Liver X Receptor (LXR) and Retinoid X Receptor (RXR);Foods;2023-11-22

5. Pyrazole appended hetero-hybrids: Bioisosteric design, synthesis, in silico and in vitro antibacterial and anti-inflammatory evaluations;Journal of Molecular Structure;2023-10

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