Safety, Pharmacokinetics, and Pharmacodynamics of Single Doses of LXR-623, a Novel Liver X-Receptor Agonist, in Healthy Participants
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Reference29 articles.
1. Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers;Repa;Science,2000
2. Role of LXRs in control of lipogenesis;Schultz;Genes Dev,2000
3. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor;Costet;J Biol Chem,2000
4. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes;Laffitte;Proc Natl Acad Sci USA,2001
5. Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element;Luo;J Clin Invest,2000
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