BmKK2, a thermostable Kv1.3 blocker from Buthus martensii Karsch (BmK) scorpion, inhibits the activation of macrophages via Kv1.3-NF-κB- NLRP3 axis-Reference-Cited by-同舟云学术

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BmKK2, a thermostable Kv1.3 blocker from Buthus martensii Karsch (BmK) scorpion, inhibits the activation of macrophages via Kv1.3-NF-κB- NLRP3 axis

Published:2023-10 Issue: Volume:314 Page:116624
ISSN:0378-8741
Container-title:Journal of Ethnopharmacology
language:en
Short-container-title:Journal of Ethnopharmacology

Author:

Wang Zhiheng,Sang Ming,Zhang Yuxin,Chen Shengjun,Li Song,Chen Yonggen,Xu Erjin,Zhou Qian,Xu Wenhao,Zhao Chenglei,Wang Dawei,Lu Wuguang,Cao Peng

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference30 articles.

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2. Potassium channels, memory T cells, and multiple sclerosis;Beeton;Neuroscientist,2005

3. Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases;Beeton;Inflamm. Allergy - Drug Targets,2011

4. USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3;Cai;Autophagy,2022

5. Targeting Kv1.3 channels on T cells;Carney;Nat. Resour.,2021

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Processed Buthus martensii Karsch scorpions ameliorate diet-induced NASH in mice by attenuating Kv1.3-mediated macrophage activation;Journal of Ethnopharmacology;2025-01

2. Similar neurotoxin expression profiles of traditional Chinese scorpion medicine material between juvenile and adult Mesobuthus martensii scorpions revealed by multiple strategic proteomics;Journal of Ethnopharmacology;2024-10

3. Differential potassium channel inhibitory activities of a novel thermostable degradation peptide BmKcug1a-P1 from scorpion medicinal material and its N-terminal truncated/restored peptides;Scientific Reports;2024-07-12

4. F1 fraction isolated from Mesobuthus eupeus scorpion venom induces macrophage polarization toward M1 phenotype and exerts anti-tumoral effects on the CT26 tumor cell line;International Immunopharmacology;2024-05

5. Kv1.3 in the spotlight for treating immune diseases;Expert Opinion on Therapeutic Targets;2024-02

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