A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway-Reference-Cited by-同舟云学术

A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway

Published:2023-03 Issue: Volume:303 Page:115933
ISSN:0378-8741
Container-title:Journal of Ethnopharmacology
language:en
Short-container-title:Journal of Ethnopharmacology

Author:

Lin Fei,Zhang Guanglin,Yang Xihan,Wang Mengshi,Wang Ruixuan,Wan Meiqi,Wang Jinyu,Wu Bo,Yan Tingxu,Jia Ying

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference66 articles.

1. American Cancer Society-Facts and Figures- 2021;Atlanta,2021

2. 5-Fluorouracil resistance mechanisms in colorectal cancer: from classical pathways to promising processes;Blondy;Cancer Sci.,2020

3. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries (vol 68, pg 394, 2018);Bray;Ca-a Cancer J. Clinicians,2020

4. Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020;Cao;Chinese Med J,2021

5. Deoxycholic acid mediates non-canonical EGFR-MAPK activation through the induction of calcium signaling in colon cancer cells;Centuori;Biochim. Biophys. Acta,2016

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploring the association between inflammatory biomarkers and gastric cancer development: A two-sample mendelian randomization analysis.;Medicine;2024-02-02

2. Exploring the pharmacological and molecular mechanisms of Salvia chinensis Benth in colorectal cancer: A network pharmacology and molecular docking study;Medicine;2023-12-15

3. A real-world study and network pharmacology analysis of EGFR-TKIs combined with ZLJT to delay drug resistance in advanced lung adenocarcinoma;BMC Complementary Medicine and Therapies;2023-11-21

4. Novel Siglec-15-Sia axis inhibitor leads to colorectal cancer cell death by targeting miR-6715b-3p and oncogenes;Frontiers in Immunology;2023-10-06

5. A network pharmacology approach to investigate dehydrocostus lactone inhibits the proliferation and epithelial-mesenchymal transition of human gastric cancer cells via regulating the PI3K/Akt and extracellular signal-regulated kinases/mitogen-activated protein kinase signalling pathways;Journal of Pharmacy and Pharmacology;2023-07-04