Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage

Author:

Jung Chang Hwa,Jung Hee,Shin Yong-Cheol,Park Jong-Hyeong,Jun Chan-Yong,Kim Hyung-Min,Yim Hee-Sun,Shin Min-Gyu,Bae Hyun-Soo,Kim Sung-Hoon,Ko Seong-Gyu

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference20 articles.

1. Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kB activation in RAW 264 7 cells;Ahn;Life Science,2005

2. IFN-γ+LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38mapk in a mouse macrophage cell line;Chan;American Journal of Physiology Cell physiology,2001

3. p38 but not p44/42 mitogen-activated protein kinase is required for nitric oxide synthase induction mediated by lipopolysaccharide in RAW 264.7 macrophages;Chen;Molecular Pharmacology,1999

4. Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look;Davydov;Journal of Ethnopharmacology,2000

5. Molecular mechanisms of macrophage activation and deactivation by Lipopolysaccharide: roles of the receptor complex;Fujihara;Pharmacology and Therapeutics,2003

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