Effective fraction of Gualou-Xiebai-Banxia decoction inhibits the apoptosis of myocardial cells induced by ox-LDL via FGF21/FGFR1/βKlotho-FRS2α signal pathway
Author:
Funder
National Natural Science Foundation of China
Natural Science Foundation of Shandong Province
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference27 articles.
1. Short-term hypoxia reverses ox-LDL-induced CD36 and GLUT4 switching metabolic pathways in H9c2 cardiomyoblast cells;Chen;J. Cell. Biochem.,2017
2. Gualou-Xiebai-Banxia decoction protects against type II diabetes with acute myocardial ischemia by attenuating oxidative stress and apoptosis via PI3K/Akt/eNOS signaling;Fu;Chin. J. Nat. Med.,2021
3. The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes;Gaich;Cell Metabol.,2013
4. The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic;Geng;Nat. Rev. Endocrinol.,2020
5. FGF21-Sirtuin 3 Axis confers the protective effects of exercise against diabetic cardiomyopathy by governing mitochondrial integrity;Jin;Circulation,2022
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