The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.nature.com/articles/s41574-020-0386-0.pdf
Reference151 articles.
1. Hui, Q., Jin, Z., Li, X., Liu, C. & Wang, X. FGF family: from drug development to clinical application. Int. J. Mol. Sci. 19, 1875 (2018).
2. Degirolamo, C., Sabba, C. & Moschetta, A. Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23. Nat. Rev. Drug Discov. 15, 51–69 (2016).
3. Lewis, J. E., Ebling, F. J. P., Samms, R. J. & Tsintzas, K. Going back to the biology of FGF21: new insights. Trends Endocrinol. Metab. 30, 491–504 (2019).
4. Kharitonenkov, A. et al. FGF-21 as a novel metabolic regulator. J. Clin. Invest. 115, 1627–1635 (2005). This paper is the first to discover FGF21 as a potential antidiabetic factor.
5. Keuper, M., Haring, H. U. & Staiger, H. Circulating FGF21 levels in human health and metabolic disease. Exp. Clin. Endocrinol. Diabetes. https://doi.org/10.1055/a-0879-2968 (2019).
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