The effect of TGFβRI inhibition on fibroblast heterogeneity in hypertrophic scar 2D in vitro models

Author:

Raktoe Rajiv S.ORCID,Rietveld Marion H.,Out-Luiting Jacoba J.,Kruithof-de Julio Marianna,van Zuijlen Paul P.M.,van Doorn Remco,El Ghalbzouri Abdoelwaheb

Funder

Nederlandse Brandwonden Stichting

Publisher

Elsevier BV

Subject

Critical Care and Intensive Care Medicine,Emergency Medicine,General Medicine,Surgery

Reference54 articles.

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2. Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing;Darby;Lab Invest,1990

3. Formation and function of the myofibroblast during tissue repair;Hinz;J Invest Dermatol,2007

4. TGF-β1 induces differentiation of papillary fibroblasts to reticular fibroblasts in monolayer culture but not in human skin equivalents;Janson;Eur J Dermatol,2014

5. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar;Desmoulière;Am J Pathol,1995

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