Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells-Reference-Cited by-同舟云学术

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Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells

Published:2024-05 Issue:1 Volume:155 Page:14-20
ISSN:1347-8613
Container-title:Journal of Pharmacological Sciences
language:en
Short-container-title:Journal of Pharmacological Sciences

Author:

Ma Yu,Okuda Suguru,Okanishi Hiroki,Xu Minhui,Jin Chunhuan,Endou Hitoshi,Ohgaki Ryuichi,Kanai Yoshikatsu^ORCID

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Reference29 articles.

1. Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics;Kanai;Pharmacol Ther,2022

2. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98);Kanai;J Biol Chem,1998

3. Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines;Yanagida;Biochim Biophys Acta,2001

4. Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation;Zhou;J Pharmacol Sci,2024

5. Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1;Okanishi;Cancer Metabol,2022

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