Linking the low‐density lipoprotein receptor‐binding segment enables the therapeutic 5‐YHEDA peptide to cross the blood‐brain barrier and scavenge excess iron and radicals in the brain of senescent mice-Reference-Cited by-同舟云学术

Linking the low‐density lipoprotein receptor‐binding segment enables the therapeutic 5‐YHEDA peptide to cross the blood‐brain barrier and scavenge excess iron and radicals in the brain of senescent mice

Published:2019-01 Issue:1 Volume:5 Page:717-731
ISSN:2352-8737
Container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions
language:en
Short-container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions

Author:

Zou Zhenyou¹²³,Shao Shengxi⁴,Zou Ruyi⁵,Qi Jini²,Chen Liguan⁶,Zhang Hui⁷,Shen Qiqiong²,Yang Yue⁸,Ma Liman²,Guo Ruzeng²,Li Hongwen¹,Tian Haibo¹,Li Pengxin¹,Yu Mingfang¹,Wang Lu¹,Kong Wenjuan¹,Li Caiyu¹,Yu Zhenhai¹,Huang Yuping¹,Chen Li¹,Shao Qi²,Gao Xinyan²,Chen Xiaolin²,Zhang Zhengbo²,Yan Jianguo¹,Shao Xiaoyun¹,Pan Ru¹,Xu Lu⁹,Fang Jing²,Zhao Lei⁵,Huang Yaohui⁵,Li Anqi²,Zhang Yuchong²,Huang Wenkao²,Tian Kechun²,Hu Minxin²,Xie Linchao²,Wu Lingbin²,Wu Yu²,Luo Zhen²,Xiao Wenxin²,Ma Shanshan⁵,Wang Jianan⁵,Huang Kaixin⁵,He Siyuan⁵,Yang Fan⁵,Zhou Shuni²,Jia Mo²,Zhang Hui¹⁰,Lu Hongsheng¹⁰,Wang Xinjuan²,Tan Jie¹

Affiliation:

1. Guangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical UniversityGuilinGXChina

2. Medical School of Taizhou UniversityTaizhouZJChina

3. Biochemistry DepartmentPurdue UniversityWest LafayetteUSA

4. Division of Cell and Molecular BiologyImperial College LondonLondonUnited Kingdom

5. Chemistry Engineering DepartmentShangrao Normal UniversityShangraoJXChina

6. Zhejiang Armed Police CorpsHangzhouZJChina

7. China Tobacco Gene Research Center, Zhengzhou Tobacco Research Institute of CNTCZhengzhouHNChina

8. Clinical Laboratory DepartmentWenzhou Medical UniversityZJChina

9. Clinical Laboratory of Jingyou HospitalXiaoshanZJChina

10. Pathology DepartmentAffiliated Hospital of Taizhou UniversityZJChina

Funder