Decrease in p3‐Alcβ37 and p3‐Alcβ40, products of Alcadein β generated by γ‐secretase cleavages, in aged monkeys and patients with Alzheimer's disease-Reference-Cited by-同舟云学术

Decrease in p3‐Alcβ37 and p3‐Alcβ40, products of Alcadein β generated by γ‐secretase cleavages, in aged monkeys and patients with Alzheimer's disease

Published:2019-01 Issue:1 Volume:5 Page:740-750
ISSN:2352-8737
Container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions
language:en
Short-container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions

Author:

Hata Saori¹,Omori Chiori¹²,Kimura Ayano¹,Saito Haruka¹,Kimura Nobuyuki³⁴,Gupta Veer⁵⁶⁷,Pedrini Steve⁶⁷,Hone Eugene⁶⁷,Chatterjee Pratishtha⁸,Taddei Kevin⁶,Kasuga Kensaku⁹,Ikeuchi Takeshi⁹,Waragai Masaaki¹⁰,Nishimura Masaki¹¹,Hu Anqi¹,Nakaya Tadashi¹,Meijer Laurent¹²,Maeda Masahiro¹³,Yamamoto Tohru¹¹⁴,Masters Colin L.¹⁵,Rowe Chris C.¹⁶,Ames David¹⁷¹⁸,Yamamoto Kazuo²,Martins Ralph N.⁵⁶⁷⁸,Gandy Sam¹⁹,Suzuki Toshiharu¹

Affiliation:

1. Laboratory of NeuroscienceGraduate School of Pharmaceutical Sciences, Hokkaido UniversitySapporoJapan

2. Department of Integrated BiosciencesGraduate School of Frontier Sciences, University of TokyoKashiwaJapan

3. Section of Cell Biology and Pathology Department of Alzheimer's Disease ResearchCenter for Development of Advanced Medicine for Dementia, National Center for Geriatrics and GerontologyObuJapan

4. Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and NutritionTsukubaJapan

5. Centre of Excellence for Alzheimer's Disease Research and Care, Sir James McCusker Alzheimer's Disease Research UnitEdith Cowan UniversityJoodalupWAAustralia

6. School of Medical and Health Sciences, Edith Cowan UniversityJoondalupWAAustralia

7. Co‐operative Research Centre for Mental HealthCarltonVICAustralia

8. Department of Biomedical Sciences, Faculty of Medical and Health SciencesMacquarie UniversitySydneyNSWAustralia

9. Department of Molecular GeneticsBrain Research Institute, Niigata UniversityNiigataJapan

10. Department of NeurologyHigashi Matsudo Municipal HospitalMatsudoJapan

11. Molecular Neuroscience Research Center, Shiga University of Medical ScienceOtsuJapan

12. ManRos TherapeuticsCentre de PerharidyRoscoffBretagneFrance

13. Immuno‐Biological Laboratories Co., Ltd. (IBL)FujiokaJapan

14. Department of Molecular Neurobiology, Faculty of MedicineKagawa UniversityMiki‐choKagawaJapan

15. Neurodegeneration DivisionThe Florey Institute, The University of MelbourneParkvilleVICAustralia

16. Department of Nuclear Medicine and Centre for PET, Austin HealthHeidelbergVICAustralia

17. National Ageing Research InstituteParkvilleVICAustralia

18. Academic Unit for Psychiatry of Old ageSt. George's Hospital, The University of MelbourneParkvilleVICAustralia

19. Mount Sinai Center for Cognitive Health and NFL Neurological Care, Icahn School of Medicine at Mount SinaiNew YorkNYUSA

Funder

Japan Society for the Promotion of Science London

Japan Agency for Medical Research and Development

Texas Instruments

Naito Foundation

Japan Society for the Promotion of Science

KAKENHI

JSPS

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.trci.2019.09.015

Reference39 articles.

1. The Calsyntenins—A Family of Postsynaptic Membrane Proteins with Distinct Neuronal Expression Patterns

2. Novel Cadherin-related Membrane Proteins, Alcadeins, Enhance the X11-like Protein-mediated Stabilization of Amyloid β-Protein Precursor Metabolism

3. Calsyntenin-1, a Proteolytically Processed Postsynaptic Membrane Protein with a Cytoplasmic Calcium-Binding Domain

4. Calsyntenin-1 Docks Vesicular Cargo to Kinesin-1

5. The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport

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