Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Molecular Medicine
Reference10 articles.
1. Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism;Araki;J. Biol. Chem.,2003
2. Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction;Hata;J. Biol. Chem.,2009
3. Brain p3-Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β-peptide;Hata;EMBO Mol. Med.,2023
4. Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer’s disease: evidence for γ-secretase dysfunction;Hata;Ann. Neurol.,2011
5. Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer’s disease;Hata;Alzheimers Dement. (NY),2019
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging;Scientific Reports;2024-08-09
2. Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1;Molecular Biology of the Cell;2023-10-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3