NGP 555, a γ‐secretase modulator, shows a beneficial shift in the ratio of amyloid biomarkers in human cerebrospinal fluid at safe doses

Author:

Kounnas Maria Z.1,Durakoglugil Murat S.2,Herz Joachim2,Comer William T.3

Affiliation:

1. Department of PathologyUniversity of CaliforniaSan DiegoLa JollaCA

2. Department of Molecular GeneticsCenter for Translational Neurodegeneration Research, University of Texas Southwestern Medical CenterDallasTX

3. NeuroGenetic Pharmaceuticals, Inc.Rancho Santa FeCA92067‐2007

Funder

National Institutes of Health

National Institute of Aging

National Institute Neurological Disorders and Stroke

NIH

Consortium for Frontotemporal Dementia Research

Bright Focus Foundation

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical)

Reference50 articles.

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2. Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

3. Ultrastructural studies in Alzheimer's presenile studies;Terry R.;Am J Pathol,1964

4. The role of Aβ42 in Alzheimer's disease

5. Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

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