Asymmetric synthesis and absolute stereochemistry of 4,4-bis-(trifluoromethyl)imidazoline based ACAT inhibitors
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference17 articles.
1. Novel 4,4-bis(trifluoromethyl) imidazolines as stereospecific and orally active acyl coa: Cholesterol acyltransferase (ACAT) inhibitors and antihypercholesterolemic agents
2. A Facile Synthesis of 4,4-Bis(trifluoromethyl)imidazolines via a Novel Oxidative Imidazole Rearrangement
3. Singlet oxygen oxidation of pyrroles: Synthesis and chemical transformations of novel 4,4-bis(trifluoromethyl)imidazoline analogs
4. Li, H.-Y.; Delucca, I.; Drummond, S.; Boswell, G. A. submitted.
5. ACAT inhibitors as antiatherosclerotic agents: Compounds and mechanisms
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1. Electrochemical tandem trifluoromethylation of allylamines/formal (3 + 2)-cycloaddition for the rapid access to CF3-containing imidazolines and oxazolidines;Organic Chemistry Frontiers;2021
2. ACAT Inhibitors: The Search for Novel Cholesterol Lowering Agents;Mini-Reviews in Medicinal Chemistry;2013-05-01
3. ChemInform Abstract: Asymmetric Synthesis and Absolute Stereochemistry of 4,4-Bis( trifluoromethyl)imidazoline Based ACAT Inhibitors.;ChemInform;2010-08-03
4. Synthesis of Alkali Metal Carboxylates and Carboxylic Acids Using “Wet” and “Anhydrous” Alkali Metal Hydroxides;Chemical Reviews;2010-04-05
5. Imidazoles;Comprehensive Heterocyclic Chemistry III;2008
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