The modified nucleosides from the “ wobble position ” of tRNAs. The synthesis of 5-carboxymethylaminomethyluridine and 5-carboxymethylaminomethyl-2-thiouridine-Reference-Cited by-同舟云学术

The modified nucleosides from the “ wobble position ” of tRNAs. The synthesis of 5-carboxymethylaminomethyluridine and 5-carboxymethylaminomethyl-2-thiouridine

Published:1983 Issue:48 Volume:24 Page:5395-5398
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Małkiewicz A.,Sochacka E.,Sayed Ahmed A.F.,Yassin S.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference12 articles.

1. A new uridine derivative located in the anticodon of tRNA 1Gly from Bacillus subtilis

2. 5-(Carboxymethylaminomethyl)-2-thiouridine, a new modified nucleoside found at the first letter position of the anticodon

3. Modified nucleosides in transfer RNA

4. Transcription of the ‘non-transcribed’ spacer ofDrosophila melanogasterrDNA

5. Syntheses of potential antimetabolites. XX. Syntheses of 5-carbomethoxymethyl- and 5-methylaminomethyl-2-thiouridine (the "first letters" of some anticodons) and closely related nucleosides from uridine.

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1. C5-substituents of uridines and 2-thiouridines present at the wobble position of tRNA determine the formation of their keto-enol or zwitterionic forms - a factor important for accuracy of reading of guanosine at the 3′-end of the mRNA codons;Nucleic Acids Research;2017-01-13

2. The influence of the C5 substituent on the 2-thiouridine desulfuration pathway and the conformational analysis of the resulting 4-pyrimidinone products;Bioorganic & Medicinal Chemistry;2015-09

3. Site-selected incorporation of 5-carboxymethylaminomethyl(-2-thio)uridine into RNA sequences by phosphoramidite chemistry;Organic & Biomolecular Chemistry;2014

4. mt-tRNA Components: Synthesis of (2-Thio)Uridines Modified with Blocked Glycine/Taurine Moieties at C-5,1;Nucleosides, Nucleotides and Nucleic Acids;2013-11-02

5. Chemical Synthesis and Properties of 5-Taurinomethyluridine and 5-Taurinomethyl-2-thiouridine;The Journal of Organic Chemistry;2009-02-16