Synthesis of optically pure mechanism-based inhibitors of γ aminobutyric acid aminotransferase (GABA-T) via enzyme-catalyzed resolution-Reference-Cited by-同舟云学术

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Synthesis of optically pure mechanism-based inhibitors of γ aminobutyric acid aminotransferase (GABA-T) via enzyme-catalyzed resolution

Published:1993-02 Issue:8 Volume:34 Page:1239-1242
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Margolin Alexey L

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference38 articles.

1. Design of potential anticonvulsant agents: mechanistic classification of GABA aminotransferase inactivators

2. Catalytic inhibition of γ-aminobutyric acid-α-ketoglutarate transaminase of bacterial origin by 4-aminohex-5-ynoic acid, a substrate analog

3. 4-Amino-hex-5-enoic Acid, a Selective Catalytic Inhibitor of 4-Aminobutyric-Acid Aminotransferase in Mammalian Brain

4. Casara. P. US Patent 4, 454, 156, 1984.

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