Scalable Synthesis of Both Enantiomers of Vigabatrin, an Antiepileptic Drug
Author:
Affiliation:
1. Organic Chemistry Division; CSIR-National Chemical Laboratory; Dr. Homi Bhabha Road 411008 Pune India
2. Academy of Scientific and Innovative Research (AcSIR); 110 025 New Delhi India
Funder
Science and Engineering Research Board
Publisher
Wiley
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ejoc.201801617/fullpdf
Reference46 articles.
1. GABA in Epilepsy: The Pharmacologic Basis
2. 4-Amino-hex-5-enoic Acid, a Selective Catalytic Inhibitor of 4-Aminobutyric-Acid Aminotransferase in Mammalian Brain
3. Mechanisms of inactivation of .gamma.-aminobutyric acid aminotransferase by the antiepilepsy drug .gamma.-vinyl GABA (vigabatrin)
4. The inhibitory action of β-hydroxy-γ-aminobutyric acid upon the seizure following stimulation of the motor cortex of the dog
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