Specifically altered metaphase chromosomes in antifolate-resistant Chinese hamster cells that overproduce dihydrofolate reductase

Author:

Biedler June L.,Melera Peter W.,Spengler Barbara A.

Publisher

Elsevier BV

Subject

Cancer Research,Genetics,Molecular Biology

Reference35 articles.

1. Mechanisms of resistance;Brockman,1975

2. The chromosomal status of drug resistant sublines of mouse leukemia L1210;Bieselle,1959

3. Selection of chromosomal variant in amethopterin-resistant sublines of leukemia L1210 with increased levels of dihydrofolate reductase;Biedler;J Natl Cancer Inst,1963

4. Association of increased dihydrofolate reductase levels and chromosome alteration in amethopterin-resistant sublines of leukemia L1210;Schrecker;J Natl Cancer Inst,1963

5. Cytogenetics of mouse leukemia L1210. I. Association of a specific chromosome with dihydrofolate reductase activity in amethopterin-treated sublines;Biedler;Cancer Res,1965

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