Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood-Reference-Cited by-同舟云学术

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Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood

Published:2012-12 Issue:4 Volume:14 Page:722-728
ISSN:1567-5769
Container-title:International Immunopharmacology
language:en
Short-container-title:International Immunopharmacology

Author:

Schmohl Michael,Schneiderhan-Marra Nicole,Baur Nadja,Hefner Kathrin,Blum Michael,Stein Gerburg M.,Joos Thomas O.,Schmolz Manfred

Funder

German Federal Ministry of Education and Research

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference38 articles.

1. Pharmacokinetics and toxicology of therapeutic proteins: advances and challenges;Vugmeyster;World J Biol Chem,2012

2. Safety of biologics, lessons learnt from TGN1412;Stebbings;Curr Opin Biotechnol,2009

3. Functional drug candidate profiling using complex human organotypic cell culture models: a promising way to reduce clinical drug failure;Schmolz;Expert Opin Drug Discov,2007

4. Human whole blood assay for rapid and routine testing of non-steroidal anti-inflammatory drugs (NSAIDs) on cyclo-oxygenase-2 activity;Laufer;Inflammopharmacology,2008

5. “Cytokine storm” in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics;Stebbings;J Immunol,2007

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