Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma
Author:
Funder
National Institutes of Health
Mayo Clinic Center for Cell Signaling in Gastroenterology
The Cholangiocarcinoma Foundation
Mayo Clinic Cancer Center
Mayo Foundation
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference31 articles.
1. Changing pattern of epidemiology in intrahepatic cholangiocarcinoma;Njei;Hepatology,2014
2. Mining CK2 in cancer;Ortega;PLoS One,2014
3. Protein kinase CK2 signal in neoplasia;Tawfic;Histol Histopathol,2001
4. CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy;Siddiqui-Jain;Cancer Res,2010
5. Overexpressions of CK2beta and XIAP are associated with poor prognosis of patients with cholangiocarcinoma;Zhou;Pathol Oncol Res,2014
Cited by 38 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells;Science Advances;2024-05-24
2. Casein Kinase 2 (CK2): A Possible Therapeutic Target in Acute Myeloid Leukemia;Cancers;2023-07-21
3. Cdc2-like kinases: structure, biological function, and therapeutic targets for diseases;Signal Transduction and Targeted Therapy;2023-04-07
4. Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2;ACS Medicinal Chemistry Letters;2023-03-14
5. Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective;Journal of Medicinal Chemistry;2023-03-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3