Clinical Implications and Translation of an Off-Target Pharmacology Profiling Hit: Adenosine Uptake Inhibition In Vitro
Author:
Funder
Amgen Inc
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference26 articles.
1. Reducing safety-related drug attrition: the use of in vitro pharmacological profiling;Bowes;Nat Rev Drug Discov,2012
2. Potential functional and pathological side effects related to off-target pharmacological activity;Lynch;J Pharmacol Toxicol Meth,2017
3. In vitro secondary pharmacological profiling: An IQ-DruSafe industry survey on current practices;Valentin;J Pharmacol Toxicol Meth,2018
4. A semi-quantitative translational pharmacology analysis to understand the relationship between in vitro ENT1 inhibition and the clinical incidence of dyspnoea and bronchospasm;Rosenbrier-Ribeiro;Toxicol Appl Pharmacol,2017
5. Secondary pharmacology data to assess potential off-target activity of new drugs: a regulatory perspective;Papoian;Nat Rev Drug Discov,2015
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Preclinical mitigation of 5-HT2B agonism-related cardiac valvulopathy revisited;Journal of Pharmacological and Toxicological Methods;2024-07
2. Preclinical Mitigation of 5-Ht2b Agonism-Related Cardiac Valvulopathy Revisited;2024
3. Migraine signaling pathways: purine metabolites that regulate migraine and predispose migraineurs to headache;Molecular and Cellular Biochemistry;2023-03-22
4. Zebrafish toxicological screening could aid Leishmaniosis drug discovery;Laboratory Animal Research;2021-09-16
5. Safety pharmacology during the COVID pandemic;Journal of Pharmacological and Toxicological Methods;2021-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3