Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS)
Author:
Funder
Medical Research Council
Publisher
Elsevier BV
Subject
Cancer Research,Genetics,Molecular Biology,Molecular Medicine
Reference46 articles.
1. Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110α and p110β catalytic subunits of class-Ia phosphoinositide 3-kinases;Beeton;Biochem J,2000
2. The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors;Berndt;Nat Chem Biol,2010
3. Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 subunit of phosphatidylinositol 3-kinase;Breeze;Embo J,1996
4. Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery;Brown;BMC Evol Biol,2011
5. Dynamics of the phosphoinositide 3-Kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α;Burke;Structure,2011
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