P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice

Author:

Chatterjee Saurabh,Rana Ritu,Corbett Jean,Kadiiska Maria B.,Goldstein Joyce,Mason Ronald P.

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference54 articles.

1. Nonalcoholic fatty liver disease: from steatosis to cirrhosis;Farrell;Hepatology,2006

2. Hepatic complications of obesity;Diehl;Gastroenterol. Clin. North Am.,2010

3. Role of mitochondria in non-alcoholic fatty liver disease;Pessayre;J. Gastroenterol. Hepatol.,2007

4. Amiodarone inhibits the mitochondrial beta-oxidation of fatty acids and produces microvesicular steatosis of the liver in mice;Fromenty;J. Pharmacol. Exp. Ther.,1990

5. Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II;Fromenty;J. Pharmacol. Exp. Ther.,1990

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