Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease

Author:

Dunn Laura,Allen George FG.,Mamais Adamantios,Ling Helen,Li Abi,Duberley Kate E.,Hargreaves Iain P.,Pope Simon,Holton Janice L.,Lees Andrew,Heales Simon J.,Bandopadhyay Rina

Funder

Rapid Response Innovation Award

Fox Foundation for Parkinson's Research

Parkinson's UK grant

Michael J Fox Foundation

Reta Lila Weston Trust

Progressive Supranuclear Palsy (Europe) Association

Reta Lila Weston Institute Fellowship

National Institute for Health Research, Biomedical Research Unit

Wellcome Trust and Medical Research Council Joint Call in Neurodegeneration award

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Neurology (clinical),Aging,General Neuroscience

Reference38 articles.

1. Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra;Alam;J. Neurochem.,1997

2. Oxidative stress in the central nervous system: monitoring the metabolic response using the pentose phosphate pathway;Ben-Yoseph;Dev. Neurosci.,1994

3. Persistent mitochondrial damage by nitric oxide and its derivatives: neuropathological implications;Bolanos;Front Neuroenergetics,2010

4. Perfusion and metabolism imaging studies in Parkinson's disease;Borghammer;Dan. Med. J.,2012

5. Staging of brain pathology related to sporadic Parkinson's disease;Braak;Neurobiol. Aging,2003

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