In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases-Reference-Cited by-同舟云学术

In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases

Published:2012-08 Issue:8 Volume:33 Page:1816-1828
ISSN:0197-4580
Container-title:Neurobiology of Aging
language:en
Short-container-title:Neurobiology of Aging

Author:

Diaz-Hernandez Juan Ignacio,Gomez-Villafuertes Rosa,León-Otegui Miriam,Hontecillas-Prieto Lourdes,del Puerto Ana,Trejo Jose Luis,Lucas Jose Javier,Garrido Juan Jose,Gualix Javier,Miras-Portugal Maria Teresa,Diaz-Hernandez Miguel

Funder

MICINN

CAM

SICI

UCM-Santander Central Hispano Bank

Fundación Marcelino Botín

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Neurology (clinical),Aging,General Neuroscience

Reference50 articles.

1. In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta;Aplin;J. Neurochem,1996

2. Physiology and pathophysiology of purinergic neurotransmission;Burnstock;Physiol. Rev,2007

3. P2Y receptor linked to phospholipase C: stimulation of neuro 2A cells by UTP and ATP and possible regulation by protein kinase C subtype epsilon;Chen;J. Neurochem,1997

4. Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease;Christie;Am. J. Pathol,1996

5. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B;Cross;Nature,1995

Cited by 159 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New Insights into Microglia as Therapeutic Targets in Alzheimer’s Disease;Current Drug Therapy;2024-03

2. Role and therapeutic targets of P2X7 receptors in neurodegenerative diseases;Frontiers in Immunology;2024-02-02

3. Increased regional P2X7R uptake detected by [¹⁸F]GSK1482160 PET in a tauopathy mouse model;2024-01-28

4. Lacking P2X7-receptors protects substantia nigra dopaminergic neurons and hippocampal-related cognitive performance from the deleterious effects of high-fat diet exposure in adult male mice;Frontiers in Nutrition;2024-01-25

5. P2X7 Receptor: an Emerging Target in Alzheimer’s Disease;Molecular Neurobiology;2023-11-09