C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins

Author:

Anderson Edward N.ORCID,Corkins Mark E.,Li Jia-Cheng,Singh Komudi,Parsons Sadé,Tucey Tim M.,Sorkaç Altar,Huang Huiyan,Dimitriadi Maria,Sinclair David A.,Hart Anne C.

Funder

Ellison Medical Foundation

National Institutes of Health

Publisher

Elsevier BV

Subject

Developmental Biology,Ageing

Reference61 articles.

1. The use of FUdR can cause prolonged longevity in mutant nematodes;Aitlhadj;Mech. Ageing Dev.,2010

2. A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans;Angeli;Aging (Albany, NY),2013

3. Regulation of life-span by germ-line stem cells in Caenorhabditis elegans;Arantes-Oliveira;Science,2002

4. Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity;Arum;J. Gerontol. Ser. A Biol. Sci. Med. Sci.,2007

5. Fluorodeoxyuridine enhances the heat shock response and decreases polyglutamine aggregation in an HSF-1-dependent manner in Caenorhabditis elegans;Brunquell;Mech. Ageing Dev.,2014

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