Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

Author:

Carazo Alejandro,Hyrsova Lucie,Dusek Jan,Chodounska Hana,Horvatova Alzbeta,Berka Karel,Bazgier Vaclav,Gan-Schreier Hongying,Chamulitrat Waleé,Kudova Eva,Pavek Petr

Funder

GACR

DFG

IGA PrF

Charles University

TACR

RVO

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference32 articles.

1. Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative;Adachi;J. Lipid Res.,2005

2. Recent advances in the development of farnesoid X receptor agonists;Ali;Ann. Transl. Med.,2015

3. Targeting xenobiotic receptors PXR and CAR in human diseases;Banerjee;Drug Discov. Today,2015

4. The role of CYP3A4 in the biotransformation of bile acids and therapeutic implication for cholestasis;Chen;Ann. Transl. Med.,2014

5. Pregnane X receptor as a target for treatment of inflammatory bowel disorders;Cheng;Trends Pharmacol. Sci.,2012

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