Contribution of human esterases to the metabolism of selected drugs of abuse

Author:

Meyer Markus R.,Schütz Aline,Maurer Hans H.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference25 articles.

1. Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs;Brzezinski;Drug Metab. Dispos.,1997

2. Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin;Hatfield;Br. J. Pharmacol.,2010

3. Human carboxylesterase isozymes: catalytic properties and rational drug design;Imai;Drug Metab. Pharmacokinet.,2006

4. Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine;Imai;Drug Metab. Dispos.,2006

5. Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases;Kamendulis;J. Pharmacol. Exp. Ther.,1996

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