A new photosafety screening strategy based on in chemico photoreactivity and in vitro skin exposure for dermally-applied chemicals

Author:

Iyama Yosuke,Sato Hideyuki,Seto Yoshiki,Onoue Satomi

Funder

The Ministry of Health, Labour and Welfare, Japan; a Grant-in-Aid for Scientific Research

Ministry of Education, Culture, Sports, Science and Technology, Japan

Research on Regulatory Science of Pharmaceuticals and Medical Devices

Japan Agency for Medical Research and Development, AMED; and a grant from the Cosmetology Research Foundation

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference34 articles.

1. Role of type I & type II reactions in DNA damage and activation of caspase 3 via mitochondrial pathway induced by photosensitized benzophenone;Amar;Toxicol. Lett.,2015

2. Testing for the equality of area under the curves when using destructive measurement techniques;Bailer;J. Pharmacokinet. Biopharm.,1988

3. Investigation of the efficacy of transdermal penetration enhancers through the use of human skin and a skin mimic artificial membrane;Balazs;J. Pharm. Sci.,2016

4. Directive 2003/15/EC of the European Parliament and of the Council of 27 February 2003 amending Council Directive 76/768/EEC on the approximation of the laws of the member states relating to cosmetic products;European Community;Off. J. Eur. Union,2003

5. Spectrum of cross-photosensitization in 18 consecutive patients with contact photoallergy to ketoprofen: associated photoallergies to non-benzophenone-containing molecules;Durbize;Contact Derm.,2003

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