Predicted drug-induced bradycardia related cardio toxicity using a zebrafish in vivo model is highly correlated with results from in vitro tests-Reference-Cited by-同舟云学术

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Predicted drug-induced bradycardia related cardio toxicity using a zebrafish in vivo model is highly correlated with results from in vitro tests

Published:2013-01 Issue:1 Volume:216 Page:9-15
ISSN:0378-4274
Container-title:Toxicology Letters
language:en
Short-container-title:Toxicology Letters

Author:

Park Myoung Joo,Lee Kyeong-Ryoon,Shin Dae-Seop,Chun Hang-Suk,Kim Cheol-Hee,Ahn Sung-Hoon,Bae Myung Ae

Funder

Ministry of Knowledge and Economy

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference46 articles.

1. Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K+ channel blockers;Andrea;Journal of Medicinal Chemistry,2002

2. Most LQT2 mutations reduce Kv11.1 (hERG) current by class 2 (trafficking deficient) mechanism;Anderson;Circulation,2006

3. HERG-Lite®: a novel comprehensive high-throughput screen for drug-induced hERG risk;Barbara;Journal of Pharmacological and Toxicological Methods,2005

4. Trends in ion channel drug discovery: advances in screening technologies;Bennet;Trends in Biotechnology,2003

5. Development and application of fluorescence polarization assays in drug discovery;Bruke;Combinatorial Chemistry & High Throughput Screening,2003

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