The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study-Reference-Cited by-同舟云学术

The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study

Published:2014-03 Issue:2 Volume:68 Page:212-221
ISSN:0273-2300
Container-title:Regulatory Toxicology and Pharmacology
language:en
Short-container-title:Regulatory Toxicology and Pharmacology

Author:

Ball Nicholas,Bartels Michael,Budinsky Robert,Klapacz Joanna,Hays Sean,Kirman Christopher,Patlewicz Grace

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference45 articles.

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3. BASF, 1985. Cleavage of glycol ether acetates by rat plasma in vitro. Unpublished short communication of BASF.

4. Case studies to test: a framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments;Blackburn;Regul. Toxicol. Pharmacol.,2011

5. Breslin, W.J., et al. (1990). Developmental toxicity of inhaled Dipropylene glycol monomethyl ether (DPGME) in rats and rabbits. Toxicologist 10: 39, Abstr. 154.

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