Methyl isobutyl ketone-induced hepatocellular carcinogenesis in B6C3F1 mice: A constitutive androstane receptor (CAR)-mediated mode of action-Reference-Cited by-同舟云学术

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Methyl isobutyl ketone-induced hepatocellular carcinogenesis in B6C3F1 mice: A constitutive androstane receptor (CAR)-mediated mode of action

Published:2016-11 Issue: Volume:81 Page:421-429
ISSN:0273-2300
Container-title:Regulatory Toxicology and Pharmacology
language:en
Short-container-title:Regulatory Toxicology and Pharmacology

Author:

Hughes B.J.,Thomas J.,Lynch A.M.,Borghoff S.J.,Green S.,Mensing T.,Sarang S.S.,LeBaron M.J.

Funder

American Chemical Council (ACC)

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference40 articles.

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2. Methyl isobutyl ketone exposure-related increases in specific measures of a2u-globulin (a2u) nephropathy in male rats along with in vitro evidence of reversible protein binding;Borghoff;Toxicol,2015

3. Fenaroli's Handbook of Flavor Ingredients;Burdock,2005

4. Evaluation of possible carcinogenic risk to humans based on liver tumors in rodent assays: the two-year bioassay is no longer necessary;Cohen;Toxicol. Pathol.,2010

5. Phenobarbital induces cytochrome P4501A2 hnRNA, mRNA and protein in the liver of C57BL/6J wild type and aryl hydrocarbon receptor knock-out mice;Corcos;FEBS Lett.,1998

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3. Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR);Critical Reviews in Toxicology;2021-05-28

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