1. eTOX database http://www.etoxproject.eu/or https://www.imi.europa.eu/content/etox Accessed September 2016.
2. Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP (National Toxicology Program);Ashby;Mutat. Res.,1991
3. The Benigni/Bossa Rulebase for Mutagenicity and Carcinogenicity – a Module of Toxtree;Benigni,2008
4. Estimation of toxic hazard–a decision tree approach;Cramer;Fd. Cosmet. Toxicol.,1978
5. Draft Reflection Paper “Current Regulatory Testing Requirements for Medicinal Products for Human Use and Opportunities for Implementation of the 3Rs”;EMA CHMP,2016