Improving acarbose production and eliminating the by-product component C with an efficient genetic manipulation system of Actinoplanes sp. SE50/110

Author:

Zhao Qinqin,Xie Huixin,Peng Yao,Wang Xinran,Bai Linquan

Funder

National Natural Science Foundation of China

Ministry of Science and Technology of China

Publisher

Elsevier BV

Subject

Genetics,Applied Microbiology and Biotechnology,Biomedical Engineering,Structural Biology

Reference40 articles.

1. Biotechnology and molecular biology of the α-glucosidase inhibitor acarbose;Wehmeier;Appl Microbiol Biotechnol,2004

2. Pharmacokinetics of acarbose. Part I: absorption, concentration in plasma, metabolism and excretion after single administration of 14C acarbose to rats, dogs and man;Ahr;Arzneimittelforschung,1989

3. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030;Whiting;Diabetes Res Clin Pract,2011

4. A new microtiter plate-based screening method for microorganisms producing α-amylase inhibitors;Feng;Biotechnol Bioproc E,2011

5. Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine;Sun;J Microbiol Biotechnol,2012

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