Thymidine kinase deficient cells with decreased TTP pools are hypersensitive to DNA alkylating agents

Author:

Wakazono Yoshihiro,Kubota Masaru,Furusho Kenshi,Liu Lili,Gerson Stanton L.

Publisher

Elsevier BV

Subject

Genetics,Toxicology,Molecular Biology

Reference29 articles.

1. Expression of thymidine kinase is essential to low dose radiation resistance of rat glioma cells;Al-Nabulsi;Cancer Res.,1994

2. Unusual sensitivity to bleomycin and joint resistance to 9-β-D-arabino-furanosyladenine and 1-β-D-furanosylcytosine of mouse FM3A cell mutants with altered ribonucleotide reductase and thymidylate synthase;Ayusawa;Cancer Res.,1983

3. Modulation of ethylnitrosourea-induced toxicity and mutagenicity in human cells by O6-benzylguanine;Bronstein;Cancer Res.,1992

4. Differences in deoxy-adenosine metabolism in human and mouse lymphocytes;Carson;J. Immunol.,1980

5. Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents;Dolan,1990

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