Immune response with long-term memory triggered by amorphous aggregates of misfolded anti-EGFR VHH-7D12 is directed against the native VHH-7D12 as well as the framework of the analogous VHH-9G8
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science,General Medicine,Biotechnology
Reference56 articles.
1. Immunogenicity of therapeutic proteins: clinical implications and future prospects;Schellekens;Clin Ther,2002
2. Bioequivalence and the immunogenicity of biopharmaceuticals;Schellekens;Nat. Rev. Drug Discovery,2002
3. Factor VIII immunogenicity;Jacquemin;Haemophilia,1998
4. Molecular mechanisms of inhibitor development in hemophilia;Tieu;Mediterr J Hematol Infect Dis,2020
5. The impact of antibodies on clinical outcomes in diseases treated with therapeutic protein: lessons learned from infantile Pompe disease;Banugaria;Genet Med,2011
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Analysis of EGFR binding hotspots for design of new EGFR inhibitory biologics;Protein Science;2024-09-14
2. Antisera Produced Using an E. coli-Expressed SARS-CoV-2 RBD and Complemented with a Minimal Dose of Mammalian-Cell-Expressed S1 Subunit of the Spike Protein Exhibits Improved Neutralization;International Journal of Molecular Sciences;2023-06-24
3. Biophysical and biochemical nature of amorphous protein oligomers determines the strength of immune response and the generation of T‐cell memory;The FEBS Journal;2023-06-21
4. The Immunogenicity of DENV1–4 ED3s Strongly Differ despite Their Almost Identical Three-Dimensional Structures and High Sequence Similarities;International Journal of Molecular Sciences;2023-01-25
5. The biophysical nature and not only the size of protein aggregates determines the strength of the immune response against dengue ED3;2022-11-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3