Efficient establishment of reactivatable latency by an acyclovir-resistant herpes simplex virus 1 thymidine kinase substitution mutant with reduced neuronal replication
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Virology
Reference58 articles.
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3. Genotypic characterization of UL23 thymidine kinase and UL30 DNA polymerase of clinical isolates of herpes simplex virus: natural polymorphism and mutations associated with resistance to antivirals;Burrel;Antimicrob. Agents Chemother.,2010
4. Human thymidine kinase can functionally replace herpes simplex virus type 1 thymidine kinase for viral replication in mouse sensory ganglia and reactivation from latency upon explant;Chen;J. Virol.,1998
5. Failure of thymidine kinase-negative herpes simplex virus to reactivate from latency following efficient establishment;Chen;J. Virol.,2004
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