Identification of natural allosteric inhibitor for Akt1 protein through computational approaches and in vitro evaluation-Reference-Cited by-同舟云学术

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Identification of natural allosteric inhibitor for Akt1 protein through computational approaches and in vitro evaluation

Published:2017-03 Issue: Volume:96 Page:200-213
ISSN:0141-8130
Container-title:International Journal of Biological Macromolecules
language:en
Short-container-title:International Journal of Biological Macromolecules

Author:

Pragna Lakshmi T.,Kumar Amit,Vijaykumar Veena,Natarajan Sakthivel,Krishna Ramadas

Funder

IPLS (DBT-BUILDER) programme, New Delhi, India

DST-FIST

UGC-Special Assitsant Programme (SAP) in Biotechnology

Publisher

Elsevier BV

Subject

Molecular Biology,General Medicine,Biochemistry,Structural Biology

Reference43 articles.

1. PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes

2. The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module

3. Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation

4. The PI3K/AKT Pathway as a Target for Cancer Treatment

5. The PI3K/AKT/mTOR pathway in breast cancer: targets, trials and biomarkers

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1. Deciphering the cytotoxic potential of acamprosate and acamprosate loaded mesoporous silica nanoparticles in hepatocellular carcinoma: an in vitro and in silico approach;Drug Development and Industrial Pharmacy;2024-09-09

2. Integrating machine learning and high throughput screening for the discovery of allosteric AKT1 inhibitors;Journal of Biomolecular Structure and Dynamics;2023-12-14

3. Computer-Aided Identification of Kinase-Targeted Small Molecules for Cancer: A Review on AKT Protein;Pharmaceuticals;2023-07-11

4. Identification of allosteric inhibitor against AKT1 through structure-based virtual screening;Molecular Diversity;2022-12-15

5. Drug Discovery of Plausible Lead Natural Compounds That Target the Insulin Signaling Pathway: Bioinformatics Approaches;Evidence-Based Complementary and Alternative Medicine;2022-03-20

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