Imaging-based assays for investigating functions of the RNA polymerase II elongation factor Elongin and the Elongin ubiquitin ligase

Author:

Weems Juston C.,Unruh Jay R.,Slaughter Brian D.,Conaway Ronald C.,Conaway Joan W.

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,Molecular Biology

Reference29 articles.

1. UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in cockayne syndrome cells;Bregman;Proc. Natl. Acad. Sci. U.S.A.,1996

2. In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin;Nguyen;Nucleic Acids Res.,1996

3. Ultraviolet radiation-induced ubiquitination and proteasomal degradation of the large subunit of RNA polymerase II. Implications for transcription-coupled DNA repair;Ratner;J. Biol. Chem.,1998

4. RNA polymerase II stalled on a DNA template during transcription elongation is ubiquitinated and the ubiquitination facilitates displacement of the elongation complex;Yang;Int. J. Oncol.,2003

5. RNA polymerase II blockage by cisplatin-damaged DNA. Stability and polyubiquitylation of stalled polymerase;Jung;J. Biol. Chem.,2006

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