Total synthesis of antiviral drug, nirmatrelvir (PF-07321332)

Author:

Shekhar Chandra,Nasam RajeshORCID,Paipuri Siva Ramakrishna,Kumar Prakash,Nayani KiranmaiORCID,Pabbaraja SrihariORCID,Mainkar Prathama S.,Chandrasekhar Srivari

Publisher

Elsevier BV

Reference30 articles.

1. A comparative analysis of SARS-CoV-2 antivirals characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19;de Vries;J. Virol.,2021

2. Nirmatrelvir Plus Ritonavir: First Approval;Lamb,2022

3. Discovery of ketone-based covalent inhibitors of coronavirus 3CL proteases for the potential therapeutic treatment of COVID-19;Hoffman;J. Med. Chem.,2020

4. The discovery and development of boceprevir: a novel, first-generation inhibitor of the hepatitis C virus NS3/4A serine protease;Howe;J. Clin. Transl. Hepatol.,2013

5. Gram scale solution-phase synthesis of heptapeptide side chain of teixobactin;Donikela;Synlett,2019

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