P22-25: Use of Bayesian-MCMC physiologically based kinetic modelling to quantify the consequences of human interindividual differences in kinetics for the relative potency of pyrrolizidine alkaloid N-oxides-Reference-Cited by-同舟云学术

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P22-25: Use of Bayesian-MCMC physiologically based kinetic modelling to quantify the consequences of human interindividual differences in kinetics for the relative potency of pyrrolizidine alkaloid N-oxides

Published:2023-09 Issue: Volume:384 Page:S260
ISSN:0378-4274
Container-title:Toxicology Letters
language:en
Short-container-title:Toxicology Letters

Author:

Widjaja F.,van Boekel M.A.J.S.,Wesseling S.,Rietjens I.M.C.M.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference4 articles.

1. 'The Role of Kinetics as Key Determinant in Toxicity of Pyrrolizidine Alkaloids and Their N-Oxides’;Widjaja;Planta Medica,2022

2. 'Physiologically based kinetic modelling predicts the in vivo relative potency of riddelliine N-oxide compared to riddelliine in rat to be dose dependent’;Widjaja;Archives of Toxicology,2022

3. 'Physiologically-Based Kinetic Modeling Predicts Similar In Vivo Relative Potency of Senecionine N-Oxide for Rat and Human at Realistic Low Exposure Levels’;Widjaja;Molecular Nutrition & Food Research,2023

4. 'Physiologically based kinetic modeling of senecionine N-oxide in rats as a new approach methodology to define the effects of dose and endpoint used on relative potency values of pyrrolizidine alkaloid N-oxides’;Widjaja;Frontiers in Pharmacology,2023

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