Comparison between follitropin-delta and follitropin-alfa for ovarian stimulation in context of ART is only scientifically sound and clinically relevant if individualization of starting dose is allowed in both arms!

Author:

Montenegro Gouveia SusanaORCID,Lispi Monica,D'Hooghe Thomas MaryORCID

Publisher

Elsevier BV

Subject

Developmental Biology,Reproductive Medicine,Obstetrics and Gynecology

Reference14 articles.

1. A randomized controlled trial investigating the use of a predictive nomogram for the selection of the FSH starting dose in IVF/ICSI cycles;Allegra;Reprod. Biomed. Online,2017

2. Individualized versus conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 non inferiority trial;Andersen;Fertil. Steril.,2017

3. Comment by Batista et al. regarding article “Randomized, assessor-blinded trial comparing highly purified human menotropin and recombinant follicle-stimulating hormone in high responders undergoing intracytoplasmic sperm injection;Batista;Fertility and Sterility (fertstertdialog),2021

4. Guideline on Ovarian Stimulation for IVF/ICSI;Guideline of the European Society of Human Reproduction and Embryology,2019

5. Individualization of the starting dose of follitropin delta reduces the overall OHSS risk and/or the need for additional preventive interventions: cumulative data over three stimulation cycles;Fernández-Sánchez;Reprod. Biomed. Online,2019

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