A novel GLP-1 analog, a dimer of GLP-1 via covalent linkage by a lysine, prolongs the action of GLP-1 in the treatment of type 2 diabetes-Reference-Cited by-同舟云学术

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A novel GLP-1 analog, a dimer of GLP-1 via covalent linkage by a lysine, prolongs the action of GLP-1 in the treatment of type 2 diabetes

Published:2017-02 Issue: Volume:88 Page:46-54
ISSN:0196-9781
Container-title:Peptides
language:en
Short-container-title:Peptides

Author:

Pan Yingying,Shi Siwei,Lao Xun,Zhang Jinlong,Tan Shiming,Wu Zirong,Huang Jing

Funder

National New Drug Development Program of the People’s Republic of China

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Endocrinology,Physiology,Biochemistry

Reference42 articles.

1. Glucagon-like peptide-1 (GLP-1): a gut hormone of potential interest in the treatment of diabetes;Ahren;Bioessays,1998

2. Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells;Moss;Peptides,2016

3. Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus;Tahrani;Nat. Rev. Endocrinol.,2016

4. Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates;Henderson;Diab. Obes. Metab.,2016

5. Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain;Hamilton;J. Neurosci. Res.,2011

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Sustained release of GLP-1 analog from γ-PGA-PAE copolymers for management of type 2 diabetes;Biomaterials Advances;2023-05

2. Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs;International Journal of Molecular Sciences;2021-05-27

3. New Insights into Beta-Cell GLP-1 Receptor and cAMP Signaling;Journal of Molecular Biology;2020-03

4. Novel mono-lipidated dimeric glucagon-like peptide-1 receptor agonist with improved long-acting and hypoglycemic activity;RSC Advances;2019

5. Rational design of dimeric lipidated Xenopus glucagon-like peptide 1 analogues as long-acting antihyperglycaemic agents;European Journal of Medicinal Chemistry;2018-09

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